Abstract
Modern drug therapy for peptic ulcer disease is aimed at maximum suppression of gastric acid secretion with histamine H2 receptor blockers and proton pump inhibitors of parental cells and possible complete eradication (CE) using a complex of antibacterial agents. Such a strategy for treating the disease assumes that peptic ulcer is mainly a local (local) pathological process in the stomach or duodenum, directly related to HP infection and aggression of active gastric juice.